Michelle Monje, MD, PhD, is a researcher studying a rare type of pediatric brain tumor, Diffuse Intrinsic Pontine Glioma (DIPG). This type of cancer often spreads quickly and the patient dies only months after diagnosis. The reasons for the quick metastasis have been unknown. However, parents who lost their child gave a generous donation of [...]
iMPACT is a three-year pilot program focusing on the recruitment and retention of minorities in cancer clinical trials. Its aim is to remove barriers and improve access to cancer-related clinical trials and is a partnership between nonprofit organizations and the National Cancer Moonshot. The goal is to create a program that can be replicated throughout [...]
How is it possible that a great many promising cancer drugs create a problem for research and trials?
There are many new immunotherapeutic drugs for cancer in the research pipeline. Too few patients are available to fill the clinical trials, as many are receiving treatment from physicians outside of the research institutions where trials are being held. In addition, many pharmaceutical companies are researching similar drugs, meaning there can be significant competition for [...]
In addition to its current grants to support travel, lodging and living expenses to enable research professionals from resource-poor countries to study research ethics and management, WCGF has expanded grant opportunities to include grants for salary support and Master's Theses and Doctoral Dissertations. Through the salary support grants, WCGF aims to assist faculty members in [...]
The reasons minority participants avoid clinical trials are well documented. Historical lack of consent, little diversity within the research team, and a percieved lack of relevance could all seem to push patients away. But researchers are working with community leaders, introducing trial navigators and working with doctors who have many patients from minority communities are [...]
The Food & Drug Administration (FDA) has recently released a Manual of Policies and Procedures (MAPP) for the use of an investigational drug in an emergency - whether during or outside business hours. Because of the urgent nature of these requests, the FDA reviews the applications as soon as they're received. Also, because this process [...]
Though the cells from breast cancer tumors of African American women and white women have an overwhelming number of similarities, aggressiveness of tumors and outcomes of the disease are drastically different. African American women are much more likely to be diagnosed at a younger age, and are more likely to have more aggressive types of [...]
How many types of cells are in the human body? Two hundred? More? A researcher found a new way to take a census of cells.
There are around 37 trillion cells in the human body. But those can be categorized into how many types? A simple Google search will yield a result of about 200, but some researchers, including Jay Shendure, a geneticist at the University of Washington, think that number is quite low. Therefore, Dr. Shendure has created a [...]
How can patients, who often don’t enroll in clinical trials because they are far from home, join trials that could save their lives?
As the ubiquity and growing dependability of online communication grows, telemedicine has proven to be a boon for patients, especially those in rural areas where the number of physicians is dwindling. And, as discoveries in the lab have been leading to promising medical treatments, the supply of patients hasn’t been able to meet the demand [...]
What is expanded access and how can a desperately ill patient find treatment through this process? Are there online tools available for navigating the steps needed?
Expanded access, also known as compassionate use, is a process by which a patient can petition both the maker of an experimental treatment and the US Food and Drug Administration for access to the treatment outside a clinical trial. The Regan-Udall Foundation has created an Expanded Access Navigator to educate patients and their physicians about [...]