General

What is a .@US_FDA priority review voucher and how does it expand opportunity for #medicalresearch of #rarediseases?

The priority review voucher program incentivizes pharmaceutical companies to research drugs for very rare diseases. When a drug developer researches a rare disease, a voucher is received by that organization from the FDA to move another treatment, often for a more common disease, through the regulatory process more quickly. How does this program work? http://bit.ly/2f5RXjm

October 27, 2017|General|Comments Off on What is a .@US_FDA priority review voucher and how does it expand opportunity for #medicalresearch of #rarediseases?

What kind of information can be gained from a mock clinical trial? How can this procedure help us learn about diversifying clinical trials?

Two populations in the United States - one in Altoona, Pennsylvania, the other in Atlanta, Georgia - of similar incomes, but different racial backgrounds, were enrolled in a mock clinical trial to gauge participation given several variables. Some similarities, such as requests for background information, arose in both populations. But differences in requests for amenities such [...]

October 24, 2017|General|Comments Off on What kind of information can be gained from a mock clinical trial? How can this procedure help us learn about diversifying clinical trials?

What information can the donation of one patient’s tumor yield about metastasis?

Michelle Monje, MD, PhD, is a researcher studying a rare type of pediatric brain tumor, Diffuse Intrinsic Pontine Glioma (DIPG). This type of cancer often spreads quickly and the patient dies only months after diagnosis. The reasons for the quick metastasis have been unknown. However, parents who lost their child gave a generous donation of [...]

October 20, 2017|General|Comments Off on What information can the donation of one patient’s tumor yield about metastasis?

What is the iMPACT Program and how will it bring diversity to clinical trials?

iMPACT is a three-year pilot program focusing on the recruitment and retention of minorities in cancer clinical trials. Its aim is to remove barriers and improve access to cancer-related clinical trials and is a partnership between nonprofit organizations and the National Cancer Moonshot. The goal is to create a program that can be replicated throughout [...]

October 17, 2017|General|Comments Off on What is the iMPACT Program and how will it bring diversity to clinical trials?

How is it possible that a great many promising cancer drugs create a problem for research and trials? 

There are many new immunotherapeutic drugs for cancer in the research pipeline. Too few patients are available to fill the clinical trials,  as many are receiving treatment from physicians outside of the research institutions where trials are being held. In addition, many pharmaceutical companies are researching similar drugs, meaning there can be significant competition for [...]

October 13, 2017|General|Comments Off on How is it possible that a great many promising cancer drugs create a problem for research and trials? 

Research Ethics Education a critical priority for WCGF: New Grant Opportunities Offered.

In addition to its current grants to support travel, lodging and living expenses to enable research professionals from resource-poor countries to study research ethics and management, WCGF has expanded grant opportunities to include grants for salary support and Master's Theses and Doctoral Dissertations. Through the salary support grants, WCGF aims to assist faculty members in [...]

October 11, 2017|General|Comments Off on Research Ethics Education a critical priority for WCGF: New Grant Opportunities Offered.

How are physicians and researchers working to make clinical trials more diverse?

The reasons minority participants avoid clinical trials are well documented. Historical lack of consent,  little diversity within the research team, and a percieved lack of relevance could all seem to push patients away. But researchers are working with community leaders, introducing trial navigators and working with doctors who have many patients from minority communities are [...]

October 10, 2017|General|Comments Off on How are physicians and researchers working to make clinical trials more diverse?

What’s the procedure for getting access to an investigational drug in an emergency?

The Food & Drug Administration (FDA) has recently released a Manual of Policies and Procedures (MAPP) for the use of an investigational drug in an emergency - whether during or outside business hours. Because of the urgent nature of these requests, the FDA reviews the applications as soon as they're received. Also, because this process [...]

October 6, 2017|General|0 Comments

How does breast cancer differ between white and African American women?

Though the cells from breast cancer tumors of African American women and white women have an overwhelming number of similarities, aggressiveness of tumors and outcomes of the disease are drastically different. African American women are much more likely to be diagnosed at a younger age, and are more likely to have more aggressive types of [...]

October 3, 2017|General|0 Comments

How many types of cells are in the human body? Two hundred? More? A researcher found a new way to take a census of cells.

There are around 37 trillion cells in the human body. But those can be categorized into how many types? A simple Google search will yield a result of about 200, but some researchers, including Jay Shendure, a geneticist at the University of Washington, think that number is quite low. Therefore, Dr. Shendure has created a [...]

September 29, 2017|General|Comments Off on How many types of cells are in the human body? Two hundred? More? A researcher found a new way to take a census of cells.